RT Spectral - шаблон joomla Новости

Lambda Light Chain [Lamb14]

Ref: AP10378C - Clone: Lamb14 - Host: Mouse - Method: P,F - Format: Concentrated
DS  Imagen 1   MSDS  Imagen 2
Rating: Not Rated Yet
Manufacturer: Gennova

Lambda detects surface immunoglobulin on normal and neoplastic B-cells. Lambda staining is seen in B-cell follicles of human lymphoid tissue. When studying B-cell neoplasms, the determination of light chain ratios remains the centerpiece. This is sound reasoning because most B-cell Lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda-positive cells. If only a single light-chain type is detected, a lymphoproliferative disorder is very likely. Monoclonality is determined by a kappa-lambda ratio greater than or equal to 3:1, a lambda-kappa ratio greater than or equal to 2:1, or a monoclonal population of 75% or moreof the total population.

Clone: Lamb14
Isotype: IgG2a
Immunogen: Purified human lambda light chain.
Staining pattern: Cytoplasmic.
Positive control: Tissue sample from tonsil or lymphoid nodule.

This antibody is designed for the specific localization of human lambda light chain using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.
Useful for detecting monoclonality in B cell lymphoproliferative disorders, which provides significant support diagnosis of lymphoma versus lymphoid hyperplasia or other reactive lymphadenitis, as well as in plasma cell leukemias, plasma cell dysplasias, myelomas or plasmacytomas.


There are yet no reviews for this product.