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Lambda Light Chain [Polyclonal]

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Ref: AP10061C - Clone: Polyclonal - Host: Rabbit - Method: P - Format: Concentrated
DS  Imagen 1   MSDS  Imagen 2
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Manufacturer: Gennova
Description

SUMMARY, EXPLANATION AND LIMITATIONS:
Antibody to the lambda light chain of immunoglobulin is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.  Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Polyclonal
Isotype: IgG
Immunogen: Lambda light chains purified from human Bence Jones proteins.
Staining pattern: Cytoplasmic.
Positive control: Tissue sample from tonsil.

APPLICATIONS:
This antibody is designed for the specific localization of human lambda light chain using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.
This antibody is useful for identifying leukemias, plasmacytomas and certain non-Hodgkin lymphomas. The demonstration of clonality in lymphomas infiltrating indicates that infiltration is also clonal and malignant.

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