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Myosin, Smooth Muscle [SMMS-1]

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Ref: AP10473 - Clone: SMMS-1 - Host: Mouse - Method: P - Format: Ready to use
DS  Imagen 1   MSDS  Imagen 2
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Manufacturer: Gennova
Description

SUMMARY, EXPLANATION AND LIMITATIONS:
Myosin is a 480 kDa protein known to interact with actin in muscle and in non-muscle cells. It contains two identical heavy chains (200 kDa each) and four light chains (15-26 kDa). Myosin molecules consist of two major regions: tails (rod) and heads; they aggregate into filaments through the tail region and interact with actin and with ATP through the head region. Multiple forms of myosin heavy chains exist for each muscle type-skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle. These are designated at type I (slow-twitch) and type II (fast-twitch).

Clone: SMMS-1
Isotype: IgG1
Immunogen: Human uterus smooth muscle extract.
Staining pattern: Cytoplasmic.
Positive control: Tissue sample from uterus, colon o appendix.

APPLICATIONS:
This antibody is designed for the specific localization of human myosin, smooth muscle using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.

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