SUMMARY, EXPLANATION AND LIMITATIONS:
Neuroblastoma is the most common extracranial solid cancer in infancy and childhood. It is a neuroendocrine tumor, arising from any neural crest element of the sympathetic nervous system. The incidence of Neuroblastoma is about 1 per 100,000 infants. Anti-Neuroblastoma is a monoclonal antibody produced using human Neuroblastoma tissue as a source of antigen. It recognizes an uncharacterized 57 kDa molecule. It is useful in identifying Neuroblastoma (99% (+)) and Desmoplastic Small Round-Cell Tumors (50% (+)). A small percentage of Ewing’s Sarcoma (20%) and Rhabdo myosarcomas (20%) stain positive with this antibody.
Immunogen: Human neuroblastoma tissue.
Staining pattern: Cytoplasmatic.
Positive control: Tissue sample from neuroblastoma.
This antibody is designed for the specific localization of human neuroblastoma using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.