SUMMARY, EXPLANATION AND LIMITATIONS:
Serotonin-positive cells are present in gastric, duodenal, jejunal, ileal, colonic and appendiceal mucosae. Positive cells are sparse and usually occur in the lower half of the gastric and intestinal mucosae. In the appendix, in addition to the mucosal serotonin-containing cells, there are single or small clusters of serotonin-positive cells in the sub-epithelial region of the lamina propria.
Isotype: IgG1 Kappa
Immunogen: 5-Hydroxytryptamine hydrochloride (3-(2-aminoethyl)-5-hydroxyindole; serotonin).
Staining pattern: Cytoplasmic.
Positive control: Tissue sample from appendix.
This antibody is designed for the specific localization of human serotonin using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.