SUMMARY, EXPLANATION AND LIMITATIONS:
Villin is found predominantly in epithelial cells that develop a brush border such as those in the intestinal mucosa, gall bladder, kidney proximal tubules and ductuli efferentes of the testis. It is located in the apical cytoplasm, adjacent to the villus and hence is a good indicator of cell polarity. This antibody will help detect villin in normal and uncharacterized tissues.
Immunogen: Human villin protein.
Staining pattern: Cytoplasmic.
Positive control: Tissue sample from small intestine, kidney.
This antibody is designed for the specific localization of human Villin using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.